Recorded answers
12,312 recorded answers
How to approach it
Approach the prompt as a chemistry problem hiding inside ordinary language. Begin with the outputs you could name in a sentence, then deliberately drop one level: which tissue builds it, from which precursor, under which enzyme, and what does the finished molecule get called in a metabolic index? The reveal here was plainly generated from a large compound catalogue, so breadth of coverage matters more than tidy phrasing. After a few safe everyday entries, push into pathways — lipid handling, steroid conversion, amino acid breakdown, sugar interconversion, inflammatory signalling — and give the systematic chemical name instead of the nickname. Keep every guess to a single substance, spell it the way a database would, and drop anything the body merely absorbs, receives as a medicine, or hosts from outside.
Get a hint
Body systems make a better map than single organs: digestion, circulation, hormone signalling, immune defence and waste clearance each leave distinct chemical traces that qualify as substances the body has produced.
A little more
Then move to process: whatever is built during synthesis, released during signalling, burned for energy or broken down for excretion is fair game, including short-lived intermediates that never reach an easily named fluid.
One step further
Aim for named chemical families rather than everyday words — acids, salts, alcohols, esters, sugar conjugates, glycoproteins and their carrier-bound forms — and include the long systematic names that only a metabolic database would list.
Reveal answers 12,312
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Deep Cut85points
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2Deep Cut85points
- 1-phosphatidylinositol-3-phosphate 5-kinaseDeep Cut85points
- 1-phosphatidylinositol-4-phosphate 5-kinaseDeep Cut85points
- 1-phosphatidylinositol-5-phosphate 4-kinaseDeep Cut85points
- 1-piperideine-6-carboxylateDeep Cut85points
- 1-pyrrolineDeep Cut85points
- 1-pyrroline-2-carboxylateDeep Cut85points
- 1-Pyrroline-5-carboxylic acidDeep Cut85points
- 1-radyl-2-acyl-sn-glycero-3-phosphocholineDeep Cut85points
- 1,2-dehydrosalsolinolDeep Cut85points
- 1,2-dihydroxy-5-(methylthio)pent-1-en-3-oneDeep Cut85points
- 1,2-NaphthoquinoneDeep Cut85points
- 1,2-PropanediolDeep Cut85points
- 1,3-Bisphosphoglyceric acidDeep Cut85points
- 1,3-DiaminopropaneDeep Cut85points
- 1,4-benzothiazine-O-quinonimineDeep Cut85points
- 1,4-NaphthoquinoneDeep Cut85points
- 1,5-anhydro-D-fructose reductaseDeep Cut85points
- 1,5-AnhydroglucitolDeep Cut85points
- 10-formyl-THF-glu(5)Deep Cut85points
- 10-formyl-THF-glu(6)Deep Cut85points
- 10-formyl-THF-glu(7)Deep Cut85points
- 10-FormyltetrahydrofolateDeep Cut85points
- 10-hydroperoxy-H4-neuroprostaneDeep Cut85points
- 10-hydroxy-D4-neuroprostaneDeep Cut85points
- 10-hydroxy-E4-neuroprostaneDeep Cut85points
- 10-hydroxy-octadec-(12Z)-enoate-9-beta-D-glucuronideDeep Cut85points
- 10-Hydroxydecanoic acidDeep Cut85points
- 10-peroxy-docosahexaenoateDeep Cut85points
- 10,11-dihydro-12-epi-LTB4Deep Cut85points
- 10,11-dihydro-12-oxo-LTB4Deep Cut85points
- 10,11-dihydro-12R-hydroxy-LTC4Deep Cut85points
- 10,11-dihydro-20-dihydroxy-LTB4Deep Cut85points
- 10,11-dihydro-20-trihydroxy-LTB4Deep Cut85points
- 10,11-dihydro-LTB4Deep Cut85points
- 10,11-dihydro-LTB4-CoADeep Cut85points
- 10,11-epoxy-(4Z,7Z)-hexadecadienoic acidDeep Cut85points
- 10,13,16-docosatrienoyl-CoADeep Cut85points
- 10,13,16-docosatrienoylcarnitineDeep Cut85points
- 10,13,16,19-docosatetraenoic acidDeep Cut85points
- 10,13,16,19-docosatetraenoyl-CoADeep Cut85points
- 10,13,16,19-docosatetraenoylcarnitineDeep Cut85points
- 11-carboxy-alpha-chromanolDeep Cut85points
- 11-carboxy-alpha-tocotrienolDeep Cut85points
Why these answers count
Scoring tracked obscurity rather than plausibility across 12223 recorded answers. Everyday entries — a hormone, a digestive fluid, a structural protein — drew so many identical submissions that they sank into the crowded tail, while names lifted from a comprehensive metabolic index rose to the top. The single 100-point answer, Lubricin, is a joint-lining glycoprotein most players would never reach, which is precisely why it was scarce and expensive. The 85-point band, with 11967 entries, is where the long systematic names live: (10Z,13Z,16Z)-docosatrienoic acid, (11R)-HPETE, (13Z)-octadecenoyl-CoA and dozens more fatty acid, carnitine and coenzyme A conjugates. These are genuine products of human enzymes, yet nobody writes them from memory, so few guesses matched. Only 201 answers scored 60, the consolation band for mid-rare picks. The lesson: the reveal drew on a catalogue of tens of thousands of compounds, and points rose with how unlikely a name was to be guessed rather than with how central it is to human biology.