Recorded answers
12,456 recorded answers
How to approach it
Approach the prompt as a chemistry problem hiding inside ordinary language. Begin with the outputs you could name in a sentence, then deliberately drop one level: which tissue builds it, from which precursor, under which enzyme, and what does the finished molecule get called in a metabolic index? The reveal here was plainly generated from a large compound catalogue, so breadth of coverage matters more than tidy phrasing. After a few safe everyday entries, push into pathways — lipid handling, steroid conversion, amino acid breakdown, sugar interconversion, inflammatory signalling — and give the systematic chemical name instead of the nickname. Keep every guess to a single substance, spell it the way a database would, and drop anything the body merely absorbs, receives as a medicine, or hosts from outside.
Get a hint
Body systems make a better map than single organs: digestion, circulation, hormone signalling, immune defence and waste clearance each leave distinct chemical traces that qualify as substances the body has produced.
A little more
Then move to process: whatever is built during synthesis, released during signalling, burned for energy or broken down for excretion is fair game, including short-lived intermediates that never reach an easily named fluid.
One step further
Aim for named chemical families rather than everyday words — acids, salts, alcohols, esters, sugar conjugates, glycoproteins and their carrier-bound forms — and include the long systematic names that only a metabolic database would list.
Reveal answers 12,456
- Endothelin-converting enzyme 1Deep Cut85points
- EndotheliumDeep Cut85points
- Endovascular papillary hemangioendotheliomaDeep Cut85points
- EndozepinesDeep Cut85points
- Enhancer of polycomb homolog 2Deep Cut85points
- Enhancer RNADeep Cut85points
- EnkephalinsDeep Cut85points
- EnkurinDeep Cut85points
- EnolaseDeep Cut85points
- Enolase 2Deep Cut85points
- Enoyl-[acyl-carrier-protein] reductase, mitochondrialDeep Cut85points
- Enoyl-CoA hydrataseDeep Cut85points
- Enoyl-CoA hydratase 2Deep Cut85points
- Enoyl-CoA hydratase, mitochondrialDeep Cut85points
- EnsconsinDeep Cut85points
- Enteric glial cellDeep Cut85points
- Enteric neuronDeep Cut85points
- Enterochromaffin cellDeep Cut85points
- Enterochromaffin-like cellDeep Cut85points
- EnterocyteDeep Cut85points
- EnterodiolDeep Cut85points
- Enteroendocrine cellDeep Cut85points
- EnterogastroneDeep Cut85points
- EnterolactoneDeep Cut85points
- EnterolithDeep Cut85points
- Enteropathy-associated T-cell lymphomaDeep Cut85points
- EnteropeptidaseDeep Cut85points
- EnterostatinDeep Cut85points
- ENTH domain-containing protein 1Deep Cut85points
- EnthesisDeep Cut85points
- EnvoplakinDeep Cut85points
- Envoplakin-likeDeep Cut85points
- EomesoderminDeep Cut85points
- EosinophilDeep Cut85points
- Eosinophil cationic proteinDeep Cut85points
- Eosinophil peroxidaseDeep Cut85points
- Eosinophil-derived neurotoxinDeep Cut85points
- Eosinophilic granulomaDeep Cut85points
- EotaxinDeep Cut85points
- Eotaxin-2Deep Cut85points
- Eotaxin-3Deep Cut85points
- EoxinsDeep Cut85points
- EpendymaDeep Cut85points
- Ependymal cellDeep Cut85points
- EpendymomaDeep Cut85points
- EPH receptor A1Deep Cut85points
- EPH receptor A2Deep Cut85points
- EPH receptor A3Deep Cut85points
- EPH receptor A4Deep Cut85points
- EPH receptor A5Deep Cut85points
Why these answers count
Scoring tracked obscurity rather than plausibility across 12223 recorded answers. Everyday entries — a hormone, a digestive fluid, a structural protein — drew so many identical submissions that they sank into the crowded tail, while names lifted from a comprehensive metabolic index rose to the top. The single 100-point answer, Lubricin, is a joint-lining glycoprotein most players would never reach, which is precisely why it was scarce and expensive. The 85-point band, with 11967 entries, is where the long systematic names live: (10Z,13Z,16Z)-docosatrienoic acid, (11R)-HPETE, (13Z)-octadecenoyl-CoA and dozens more fatty acid, carnitine and coenzyme A conjugates. These are genuine products of human enzymes, yet nobody writes them from memory, so few guesses matched. Only 201 answers scored 60, the consolation band for mid-rare picks. The lesson: the reveal drew on a catalogue of tens of thousands of compounds, and points rose with how unlikely a name was to be guessed rather than with how central it is to human biology.